Opioid Addiction Your Comprehensive Guide

Medical Providers:
Dr. Michael Vines, MD
Alex Spritzer, FNP, CARN-AP, PMHNP
Clinical Providers:
Natalie Foster, LPC-S, MS
Last Updated: December 16, 2022

Opioid Addiction by the Numbers

Nearly 130 Americans lose their lives each day to opioid overdoses, and in 2011, the Centers for Disease Control officially declared opioid overdoses an epidemic.

Despite recent efforts by local and federal authorities, opioid addiction continues to pose a significant challenge.

Our Opioid Treatment Programs

ChatGPT said: Take back control of your life from opioids.

Prescription opioids are typically used to manage moderate to severe chronic pain, as their chemical properties help relax and soothe the body. However, these same effects can lead to misuse and eventual addiction, even when the medication is taken exactly as prescribed.

What Are Opioids?

Opioids are a class of drugs derived from the opium poppy plant. Some are naturally extracted from the plant, while others are synthetically produced in labs using the same chemical structure. This category includes both illegal drugs, like heroin, and prescription medications, such as oxycodone.

Recovery is achievable. Support is available to guide you.

2 Types of Opioids

The opioid drug class includes a wide range of substances, some legally prescribed and others illegal.

Illegal
Opioids

Illegal opioids are often cut, or mixed, with other drugs making them more than just opioids. However, illegal opioids include:

  • Heroin
  • Opium

Prescribed
Opioids

Opioids are frequently obtained through a doctor’s prescription, and even when used as directed, they can lead to physical dependence and changes in brain chemistry. Common prescription opioids include:

  • Oxycodone
  • Hydrocodone
  • Codeine
  • Fentanyl
  • Morphine
  • More

What Do Opioids Look Like?

Prescription opioids are available in various forms, including tablets, capsules, syrups, and injectable liquids.

Opium usually appears as a fine brown powder and can be consumed orally or smoked.

Heroin, in its purest form, is a fine white powder, but it is often cut with other substances, which can turn it brown or black.

The Science Behind Pain Killers

Opioids work by activating specific receptors on nerve cells, known as opioid receptors. When these receptors are triggered, the brain’s ability to perceive pain is reduced, while feelings of pleasure are intensified.

Natural Pain Relief

These receptors are normally activated by endorphins and other naturally produced chemicals in the body. That’s why activities that boost endorphin levels, such as exercise, can help reduce pain and create a mild feeling of euphoria.

What Are Opioid Receptors?

Opioid receptors are small sites located at the ends of nerve cells that stay inactive until triggered by specific chemicals. When the body experiences pain, electrical signals are sent to the brain to communicate it. Once activated, opioid receptors block these signals, preventing them from reaching the brain and providing pain relief.

Cause of Abuse

Opioids are commonly used for pain management because of how they interact with the body. By occupying the opioid receptors, they block the normal perception of pain and trigger feelings of pleasure. It is this combination of pain relief and euphoria that gives opioids a high potential for abuse.

How Long Do Opioids Stay in Your System?

The length of time opioids remain in the body varies depending on the specific drug, dosage, individual metabolism, and the type of drug test used. Typically, opioids can be detected in urine for about 2 to 4 days, though some opioids with longer half-lives may be detectable for a longer period.

3 Components of Opioid Addiction

The addictive nature and associated risks of prescription opioids have contributed to one of the most significant health crises of the 21st century.

Tolerance

One of the earliest signs of opioid addiction is developing a tolerance to the drug. Over time, opioid use permanently alters brain chemistry, causing the body to respond less to the substance and requiring higher doses to achieve the same effects.

Withdrawal

Individuals who develop a tolerance to opioids often experience withdrawal symptoms when they stop using the drug. Common signs of opioid withdrawal include agitation, anxiety, insomnia, nausea, vomiting, and other physical and emotional challenges.

Dependence

One of the most dangerous aspects of opioid addiction is the psychological dependence that develops over time. With repeated use and increasing doses, the brain adapts to function normally only when the drug is present, leading to abnormal functioning and distress when it is not.

What is Opioid Addiction?

Opioid addiction is a chronic condition that can lead to serious health, social, and financial consequences.

People struggling with addiction often begin to prioritize obtaining and using the drug over other important aspects of their lives.


Risk Factors of Opioid Abuse

When it comes to opioids, no single group is affected more than others, but certain risk factors can increase the likelihood of addiction. If you are prescribed opioids and are concerned about your risk, you can use the assessment tool available at drugabuse.gov to evaluate your potential for dependence.

Family
History

People who have a close family member with a history of substance abuse face a greater risk of developing opioid addiction. This heightened vulnerability may result from genetic predisposition as well as emotional trauma experienced during childhood, which can contribute to using opioids as a form of self-medication.

Mental
Health

As with many types of substance abuse, existing mental health conditions can greatly heighten the risk of addiction. Disorders such as bipolar disorder, schizophrenia, or OCD are often stronger predictors of substance dependence than anxiety or depression. Those experiencing both mental health challenges and addiction typically require integrated treatment through a Dual Diagnosis Program.

Biological
Gender

Women are more susceptible to developing opioid addiction, as biological differences can cause them to become dependent more quickly than men. They are also more likely to experience chronic pain, and when prescribed opioids, tend to receive longer prescriptions and higher doses compared to men.

Opioid addiction among young adults often develops in those with multiple risk factors. During early adulthood, access to prescription pills—often from friends or family—combined with a tendency toward risk-taking behaviors makes individuals between 18 and 25 especially vulnerable to addiction.

Are you struggling with opioid addiction? We can help.

test section title

The Opioid Epidemic has impacted millions of Americans and was officially declared a national public health crisis in 2017.

Between 1997 and 2017, nearly 400,000 Americans lost their lives to opioid overdoses—more than the combined deaths from the Iraq, Vietnam, Korean, and Revolutionary Wars.

With the continued development and availability of effective addiction treatments, the number of opioid-related deaths can decline, bringing hope for an end to the epidemic. Contact our addiction specialists today to find a treatment plan that’s right for you.

Now is the moment to take the first step toward your recovery.

Diagnosing opioid addiction requires a comprehensive evaluation, which may include a urine analysis or information gathered through a Prescription Drug Monitoring Program (PDMP). Opioid use disorder is diagnosed when an individual displays two or more specific symptoms within a 12-month period, with the condition classified as severe if six or more symptoms are present.

OUD Diagnostic Criteria

  1. Continued use despite worsening physical or psychological health
  2. Continued use leading to social consequences
  3. Decreased social or recreational activities
  4. Difficulty fulfilling personal duties at work
  5. Excessive time taking opioids, or recovering from taking them
  6. Taking more than intended
  7. Unable to decrease the amount used or stop taking them
  8. A buildup of tolerance
  9. Using despite being in a dangerous setting
  10. Experiencing withdrawal symptoms

Break free from opioid addiction with support from Arizona IOP.

  • Every day, 128 people in the United States die from an opioid overdose.
  • Approximately 21% to 29% of individuals prescribed opioids for chronic pain misuse them.
  • Between 8% and 12% go on to develop an opioid use disorder.
  • Nearly 80% of people who use heroin first misused prescription opioids.

Don’t become another statistic. Take the first step toward recovery today.