Nearly 24.9% of Americans aged 12 or older—or about 70.5 million people—used illicit drugs or misused prescription drugs in the past year. Because drug use touches so many lives, it’s only natural to wonder: How long does it take for a drug to be cleared from the body? Maybe it’s for a test, your health, or because you’re considering outpatient care on your recovery path.
There’s no one-size-fits-all answer. Drug clearance time depends on the substance, dosage, and how your body metabolizes it. In this article, we’ll walk through how the body processes different drugs, clarify what “half-life” means, and outline the factors that determine how long substances can stick around. You’ll also get insight into detox timelines, how long drugs show up on tests, and how outpatient treatment can support sustainable recovery.